Nature · 2008 · 582 citations · 17 references
Life SciencesGeneticsMolecular BiologyInnate ImmunityMitochondrial BiologyMolecular ImmunologyAntiviral ImmunityMitochondrial DysfunctionMitochondrial Gene ExpressionMitochondrial PhysiologyMitochondrial SignalingMitochondrial Antiviral SignalingNlr Family RegulationNlrx1 Signaling
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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
Etienne Meylan, Joseph Curran, Kay Hofmann et al. · Nature · 2005 · 2.4K citations · Full text