Helen S. Price

Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate

Martin J. Slater, Elizabeth M. Amphlett, David Andrews et al. · Journal of Medicinal Chemistry · 2007 · 90 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors

Paul Beswick, Sharon Bingham, C. Bountra et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Pyridine-derived γ-secretase modulators

Zehong Wan, Adrian Hall, Yingxia Sang et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 29 citations · Full text

Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors

Martin E. Swarbrick, Paul Beswick, Robert J. Gleave et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach

Paul Beswick, Andrew P. Blackaby, C. Bountra et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11