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Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineNatural SciencesPharmacological AgentOrganic ChemistryPharmacotherapySelective Cyclooxygenase-2 InhibitorsDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery