Nick M. Clayton

CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain

Nick M. Clayton, Fiona H. Marshall, C. Bountra et al. · Pain · 2002 · 242 citations

Medicine, Medicinal Chemistry, Pharmacology +17

GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain

Jorge De Alba, Nick M. Clayton, S D Collins et al. · Pain · 2005 · 131 citations

Medicine, Pharmacology, Inflammation +16

Discovery of 2-[(2,4-Dichlorophenyl)amino]- <i>N</i> -[(tetrahydro- 2 <i>H</i> -pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a Selective CB2 Receptor Agonist for the Treatment of Inflammatory Pain

Gerard M.P. Giblin, Celestine T. O’Shaughnessy, Alan Naylor et al. · Journal of Medicinal Chemistry · 2007 · 120 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat

Steven J. R. Elmes, Lisa Winyard, Stephen J. Medhurst et al. · Pain · 2005 · 96 citations

Medicine, Pharmacology, Pharmacotherapy +17

Review article: the therapeutic potential of 5‐HT₃receptor antagonists in the treatment of irritable bowel syndrome

P.P.A. Humphrey, C. Bountra, Nick M. Clayton et al. · Alimentary Pharmacology & Therapeutics · 1999 · 94 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17