Martin E. Swarbrick

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib et al. · Nature Communications · 2021 · 350 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

MNK Inhibition Sensitizes <i>KRAS</i> -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression

John R. P. Knight, George Skalka, Nikola Vlahov et al. · Cancer Discovery · 2020 · 95 citations · Full text

Medicine, Molecular Biology, Oncology +17

Enantioselective Baeyer–Villiger Oxidation Catalyzed by Palladium(II) Complexes with Chiral <i>P,N</i>-Ligands

Andrei V. Malkov, Frédéric Friscourt, Mark Bell et al. · The Journal of Organic Chemistry · 2008 · 78 citations

Natural Sciences, Chemistry, Catalysis +7

Alkyl Substituent Effects on Pipecolyl Amide Isomer Equilibrium:  Efficient Methodology for Synthesizing Enantiopure 6-Alkylpipecolic Acids and Conformational Analysis of Their<i>N</i>-Acetyl<i>N</i>‘-Methylamides

Martin E. Swarbrick, Francis Gosselin, William D. Lubell · The Journal of Organic Chemistry · 1999 · 65 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain

Robert J. Gleave, Paul Beswick, Andrew J. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 44 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12