Helen M.R. Robinson

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib et al. · Nature Communications · 2021 · 350 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells

Ondrej Beláň, Marie Sebald, Marek Adamowicz et al. · Molecular Cell · 2022 · 129 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Chk1-dependent slowing of S-phase progression protects DT40 B-lymphoma cells against killing by the nucleoside analogue 5-fluorouracil

Helen M.R. Robinson, Robert H. Jones, Mark Walker et al. · Oncogene · 2006 · 51 citations

Medicine, Oncology, Pharmacology +12

Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta

Martin L. Stockley, Amanda Ferdinand, Giovanni Benedetti et al. · Journal of Medicinal Chemistry · 2022 · 43 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX

Mary Mac Partlin, Elizabeth Homer, Helen M.R. Robinson et al. · Oncogene · 2003 · 42 citations

Life Sciences, Genetics, Molecular Biology +12