Andrew P. Blackaby

Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase

Christine J. Rowe, Ines Böhm, Iain P Thomas et al. · Chemistry & Biology · 2001 · 81 citations · Full text

Biosynthesis, Extra Module, Engineering +11

Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase

Barrie Wilkinson, Graham Foster, Brian A.M. Rudd et al. · Chemistry & Biology · 2000 · 78 citations · Full text

Biosynthesis, Biochemistry, Natural Sciences +6

Identification and cloning of a type III polyketide synthase required for diffusible pigment biosynthesis in <i>Saccharopolyspora erythraea</i>^‡

Jesús Cortés, Javier Velasco, Graham Foster et al. · Molecular Microbiology · 2002 · 67 citations

Biosynthesis, Thn Biosynthesis, Engineering +13

Discovery of Novel Ansamycins Possessing Potent Inhibitory Activity in a Cell-based Oncostatin M Signalling Assay.

Paul Stead, Shazia Latif, Andrew P. Blackaby et al. · The Journal of Antibiotics · 2000 · 40 citations · Full text

Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach

Paul Beswick, Andrew P. Blackaby, C. Bountra et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 21 citations · Full text

Novel Series, Biochemistry, Medicine +9