Quorum‐sensing cross talk: isolation and chemical characterization of cyclic dipeptides from <i>Pseudomonas aeruginosa</i> and other Gram‐negative bacteria

Matthew T. G. Holden, Siri Ram Chhabra, Rocky de Nys, +12

Molecular Microbiology

<i>N</i>-(3-oxohexanoyl)-<scp>l</scp>-homoserine lactone regulates carbapenem antibiotic production in <i>Erwinia carotovora</i>

Nigel J. Bainton, Paul Stead, Siri Ram Chhabra, +4

Biochemical Journal

BiosynthesisEngineeringBiotransformationBiochemistryGroup 1 +11

A general role for the lux autoinducer in bacterial cell signalling: control of antibiotic biosynthesis in Erwinia

Nigel J. Bainton, Barrie W. Bycroft, Siri Ram Chhabra, +8

Gene

Antimicrobial Resistance GeneAntibioticsVirulence FactorBacteriologyMolecular Biology +8

Autoregulation of carbapenem biosynthesis in Erwinia carotovora by analogues of N-(3-oxohexanoyl)-L-homoserine lactone.

Siri Ram Chhabra, Paul Stead, Nigel J. Bainton, +4

The Journal of Antibiotics

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin

Peter Murray, Michael Kranz, Mark Ladlow, +11

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicine +5

Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity

Paul Stead, Phil Robinson, Nicholas B. Pike, +6

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryEryloside FBiochemistryMedicineNatural Sciences +7

Discovery of Novel Ansamycins Possessing Potent Inhibitory Activity in a Cell-based Oncostatin M Signalling Assay.

Paul Stead, Shazia Latif, Andrew P. Blackaby, +10

The Journal of Antibiotics

Efficient procedures for the large-scale preparation of (1S,2S)-trans-2-methoxycyclohexanol, a key chiral intermediate in the synthesis of tricyclic β-lactam antibiotics

Paul Stead, Hugh Marley, Mahmoud Mahmoudian, +7

Tetrahedron Asymmetry

Efficient ProceduresOrganic ChemistryTricyclic β-Lactam AntibioticsChemistryPharmacology +4

Induction of phenazine biosynthesis in cultures of<i>Pseudomonas aeruginosa</i>by L-<i>N</i>-(3-oxohexanoyl) homoserine lactone

Paul Stead, Brian A.M. Rudd, Helen Bradshaw, +2

FEMS Microbiology Letters

BacteriologyMicrobial PhysiologyAntimicrobial ChemotherapyPhenazine BiosynthesisDrug Resistance +17

A versatile procedure for the generation of nucleoside 5′-carboxylic acids using nucleoside oxidase

Mahmoud Mahmoudian, Brian A.M. Rudd, Brian J. Cox, +8

Tetrahedron

Nucleic Acid ChemistryBioorganic ChemistryEngineeringBiochemistryNatural Sciences +8