Concepedia

Pyridine-derived γ-secretase modulators

Zehong Wan, Adrian Hall, Yingxia Sang, Jia‐Ning Xiang, Eric Yang, Beverley Smith, David C. Harrison, Guang Yang, Haihua Yu, Helen S. Price,

Bioorganic & Medicinal Chemistry Letters · 2011 · 29 citations · 28 references

DOIFull text

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References

28

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Sascha Weggen, Jason L. Eriksen, Pritam Das et al. · Nature · 2001 · 1.4K citations

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Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

Bas A. in 't Veld, Annemieke Ruitenberg, Albert Hofman et al. · New England Journal of Medicine · 2001 · 1.2K citations · Full text

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Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.

Paul Aisen, Kimberly Schafer, Michael Grundman et al. · PubMed · 2003 · 968 citations

, , +17

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 879 citations · Full text

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Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent Neurodegeneration

Carlos A. Saura, Se‐Young Choi, Vassilios Beglopoulos et al. · Neuron · 2004 · 761 citations · Full text

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