Beverley Smith

The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial

David Beard, Loretta Davies, Jonathan Cook et al. · The Lancet · 2019 · 302 citations · Full text

Medicine, Orthopaedic Surgery, Surgery +15

Evaluation by patients with heart failure of the effects of enalapril compared with hydralazine plus isosorbide dinitrate on quality of life: V-HeFT II

Tom S. Rector, Gary R. Johnson, W. Bruce Dunkman et al. · Circulation · 1993 · 88 citations

Pharmacy, Pharmacology, Pharmacotherapy +16

Piperidine-derived γ-secretase modulators

Adrian Hall, Richard L. Elliott, Gerard M.P. Giblin et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 51 citations · Full text

Dynamics of Aβ42 Reduction in Plasma, CSF and Brain of Rats Treated with the γ-Secretase Modulator, GSM-10h

Julie A. Hawkins, David C. Harrison, Sharlin Ahmed et al. · Neurodegenerative Diseases · 2011 · 33 citations

Life Sciences, Neuroscience, Pharmacology +17

Discovery of <i>N</i>-(3-Fluorophenyl)-1-[(4-([(3<i>S</i>)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the First Small Molecule Motilin Receptor Agonist Clinical Candidate

Susan M. Westaway, Samantha L. Brown, Stephen C. M. Fell et al. · Journal of Medicinal Chemistry · 2009 · 29 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12