Ami S. Lakdawala

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay et al. · Molecular Cell · 2014 · 593 citations · Full text

Cell Regulation, Pronecrotic Kinase Activity, Receptor Tyrosine Kinase +6

DNA-Encoded Library Screening Identifies Benzo[<i>b</i>][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors

Philip A. Harris, Bryan W. King, Deepak Bandyopadhyay et al. · Journal of Medicinal Chemistry · 2016 · 268 citations · Full text

Drug Target, Immunology, Kinase Inhibitors +17

Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky et al. · Cancer Research · 2006 · 262 citations · Full text

Pathology, Oncogenic Braf Alleles, Tumor Biology +17

Druggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe Molecules

Ahmet Bakan, Neysa Nevins, Ami S. Lakdawala et al. · Journal of Chemical Theory and Computation · 2012 · 170 citations · Full text

Drug Target, Hit Identification, Allosteric Proteins +19

The Identification and Pharmacological Characterization of 6-( <i>tert</i> -Butylsulfonyl)- <i>N</i> -(5-fluoro-1 <i>H</i> -indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase

Pamela A. Haile, Bartholomew J. Votta, Robert W. Marquis et al. · Journal of Medicinal Chemistry · 2016 · 122 citations · Full text