Bryan W. King

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay et al. · Molecular Cell · 2014 · 593 citations · Full text

Cell Regulation, Pronecrotic Kinase Activity, Receptor Tyrosine Kinase +6

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Philip A. Harris, Scott B. Berger, Jae Uk Jeong et al. · Journal of Medicinal Chemistry · 2017 · 464 citations · Full text

Drug Target, Immunology, Cell Death +22

Asymmetric Aldol Additions:  Use of Titanium Tetrachloride and (−)-Sparteine for the Soft Enolization of <i>N-</i>Acyl Oxazolidinones, Oxazolidinethiones, and Thiazolidinethiones

Michael T. Crimmins, Bryan W. King, Elie A. Tabet et al. · The Journal of Organic Chemistry · 2001 · 384 citations

DNA-Encoded Library Screening Identifies Benzo[<i>b</i>][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors

Philip A. Harris, Bryan W. King, Deepak Bandyopadhyay et al. · Journal of Medicinal Chemistry · 2016 · 268 citations · Full text

Drug Target, Immunology, Kinase Inhibitors +17

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Melissa B. Pappalardi, Kathryn Keenan, Mark Cockerill et al. · Nature Cancer · 2021 · 251 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +9