Yongneng Zhang

High uric acid directly inhibits insulin signalling and induces insulin resistance

Yuzhang Zhu, Yaqiu Hu, Tianliang Huang et al. · Biochemical and Biophysical Research Communications · 2014 · 301 citations

Metabolic Syndrome, High Uric Acid, Insulin Signalling +8

Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic β cells

Yongneng Zhang, Tetsuya Yamamoto, Ichiro Hisatome et al. · Molecular and Cellular Endocrinology · 2013 · 124 citations

Cell Physiology, Signal Transduction, Physiology +9

Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity

Bruno Saleme, Vikram Gurtu, Yongneng Zhang et al. · Science Translational Medicine · 2019 · 83 citations

Cardiac Muscle, Heart Failure, Cell Death +19

Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state

Xiao-Qing Dai, Joan Camuñas-Soler, Linford J.B. Briant et al. · Cell Metabolism · 2022 · 80 citations · Full text

AMP-Activated Protein Kinase Suppresses the In Vitro and In Vivo Proliferation of Hepatocellular Carcinoma

Jidong Cheng, Tianliang Huang, Youfeng Li et al. · PLoS ONE · 2014 · 71 citations · Full text

Ampk Activity, Vivo Proliferation, Insulin Signaling +20