Yuzhang Zhu

High uric acid directly inhibits insulin signalling and induces insulin resistance

Yuzhang Zhu, Yaqiu Hu, Tianliang Huang et al. · Biochemical and Biophysical Research Communications · 2014 · 301 citations

Metabolic Syndrome, High Uric Acid, Insulin Signalling +8

Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic β cells

Yongneng Zhang, Tetsuya Yamamoto, Ichiro Hisatome et al. · Molecular and Cellular Endocrinology · 2013 · 124 citations

Cell Physiology, Signal Transduction, Physiology +9

High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo

Zhi Li, Yuzhang Zhu, Tianliang Huang et al. · PLoS ONE · 2016 · 107 citations · Full text

Metabolic Syndrome, Cardiomyopathy, High Uric Acid +14

AMP-Activated Protein Kinase Suppresses the In Vitro and In Vivo Proliferation of Hepatocellular Carcinoma

Jidong Cheng, Tianliang Huang, Youfeng Li et al. · PLoS ONE · 2014 · 71 citations · Full text

Ampk Activity, Vivo Proliferation, Insulin Signaling +20

Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells

Huier Yuan, Yaqiu Hu, Yuzhang Zhu et al. · Molecular and Cellular Endocrinology · 2016 · 57 citations

Metabolic Syndrome, Skeletal Muscle Cells, Molecular Physiology +10