Yaqiu Hu

High uric acid directly inhibits insulin signalling and induces insulin resistance

Yuzhang Zhu, Yaqiu Hu, Tianliang Huang et al. · Biochemical and Biophysical Research Communications · 2014 · 301 citations

Metabolic Syndrome, High Uric Acid, Insulin Signalling +8

Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells

Huier Yuan, Yaqiu Hu, Yuzhang Zhu et al. · Molecular and Cellular Endocrinology · 2016 · 57 citations

Metabolic Syndrome, Skeletal Muscle Cells, Molecular Physiology +10

Metformin inhibits estrogen‐dependent endometrial cancer cell growth by activating the <scp>AMPK</scp>–<scp>FOXO</scp>1 signal pathway

Jingfang Zou, Liangli Hong, Chaohuan Luo et al. · Cancer Science · 2016 · 50 citations · Full text

High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1

Chaohuan Luo, Xueke Lian, Liangli Hong et al. · Cellular Physiology and Biochemistry · 2016 · 45 citations · Full text

Two naturally occurring mutations in the kinase domain of insulin receptor accelerate degradation of the insulin receptor and impair the kinase activity.

Teruhiko Imamura, Yasumitsu Takata, Toshiyasu Sasaoka et al. · Journal of Biological Chemistry · 1994 · 42 citations · Full text

Molecular Biology, Insulin Receptor Gene, Insulin Receptor +20