Concepedia

High uric acid directly inhibits insulin signalling and induces insulin resistance

Yuzhang Zhu, Yaqiu Hu, Tianliang Huang, Yongneng Zhang, Zhi Li, Chaohuan Luo, Yinfeng Luo, Huier Yuan, Ichiro Hisatome, Tetsuya Yamamoto,

Biochemical and Biophysical Research Communications · 2014 · 309 citations · 31 references

DOI

Concepts

References

31

Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.3K citations · Full text

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IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Gökhan S. Hotamışlıgil, Pascal Peraldi, Adriane I. Budavari et al. · Science · 1996 · 2.6K citations

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Chronic Subclinical Inflammation as Part of the Insulin Resistance Syndrome

Andreas Festa, Ralph B. D’Agostino, George Howard et al. · Circulation · 2000 · 2.4K citations

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Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007-2008

Yanyan Zhu, Bhavik J. Pandya, Hyon K. Choi · Arthritis & Rheumatism · 2011 · 1.8K citations · Full text

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The c-Jun NH2-terminal Kinase Promotes Insulin Resistance during Association with Insulin Receptor Substrate-1 and Phosphorylation of Ser307

Vincent Aguirre, Tohru Uchida, Lynne Yenush et al. · Journal of Biological Chemistry · 2000 · 1.5K citations · Full text

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