Xiao-Qing Dai

Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes

Joan Camuñas-Soler, Xiao-Qing Dai, Yan Hang et al. · Cell Metabolism · 2020 · 282 citations · Full text

Human Islet Dysfunction, Functional Genomics, Single Cell Sequencing +11

Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx

Harini Chakravarthy, Xueying Gu, Martin Enge et al. · Cell Metabolism · 2017 · 210 citations · Full text

Both Dnmt1, Pancreatic Islet Biology, Immunology +6

Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

Martijn van de Bunt, Jocelyn E. Manning Fox, Xiao-Qing Dai et al. · PLoS Genetics · 2015 · 204 citations · Full text

Genetics, Glucose Homeostasis, Epigenetics +16

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells

Mourad Ferdaoussi, Xiao-Qing Dai, Mette V. Jensen et al. · Journal of Clinical Investigation · 2015 · 172 citations · Full text

Metabolic Remodeling, Cellular Physiology, Insulin Signaling +20

Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease

Laetitia Koppe, Elsa Nyam, Kevin Vivot et al. · Journal of Clinical Investigation · 2016 · 158 citations · Full text

Glucose Homeostasis, Insulin Signaling, Glomerulonephritis +21