Amanda L. Christie

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.2K citations · Full text

Bet Bromodomains, Genetics, Pathogenesis +3

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama et al. · Nature · 2011 · 628 citations · Full text

Signaling Pathway, Cell Regulation, Apoptosis +6

Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

Yu‐Tzu Tai, Patrick A. Mayes, Chirag Acharya et al. · Blood · 2014 · 472 citations

Mediator kinase inhibition further activates super-enhancer-associated genes in AML

Henry E. Pelish, Brian B. Liau, I Niţulescu et al. · Nature · 2015 · 391 citations · Full text

Mediator Kinase Inhibition, Transcriptional Regulation, Signal Transduction +5

The Requirement for Cyclin D Function in Tumor Maintenance

Yoon Jong Choi, Xiaoyu Li, Per Hydbring et al. · Cancer Cell · 2012 · 345 citations · Full text

Oncology, Medicine, Pathology +6