Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

Yu‐Tzu Tai, Patrick A. Mayes, Chirag Acharya, +14

Blood

The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4

Li Liu, Patrick A. Mayes, Stephen D. Eastman, +12

Clinical Cancer Research

ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation

Guoliang Qing, Bo Li, Annette Vu, +9

Cancer Cell

Cell RegulationApoptosisCell DeathTumor SuppressorMedicine +4

Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects

Joshua E. Allen, Gabriel Krigsfeld, Patrick A. Mayes, +10

Science Translational Medicine

Integrative genomics identifies LMO1 as a neuroblastoma oncogene

Kai Wang, Sharon J. Diskin, Haitao Zhang, +30

Nature

Neuroblastoma OncogeneCancer GenomicsCancer GeneticsMedicineCell Biology +1

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

Kristina A. Cole, Jonathan H. Huggins, Michael P. LaQuaglia, +14

Proceedings of the National Academy of Sciences

Rnai ScreenProtein Kinome IdentifiesTotal MycGliomaChildhood Cancer +11

Evaluation of B cell maturation antigen as a target for antibody drug conjugate mediated cytotoxicity in multiple myeloma

Lydia Lee, Danton Bounds, Jennifer C. Paterson, +11

British Journal of Haematology

ImmunologyPathologyImmunotherapyTumor BiologyMyeloid Neoplasia +14

Combinatorial Regulation of Neuroblastoma Tumor Progression by N-Myc and Hypoxia Inducible Factor HIF-1α

Guoliang Qing, Nicolas Skuli, Patrick A. Mayes, +4

Cancer Research

PathologyCancer BiologyTumor BiologyHypoxia ResponsesOncology +14

TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death

Kageaki Kuribayashi, Gabriel Krigsfeld, Wenge Wang, +5

Cancer Biology & Therapy

ApoptosisImmunologyCell DeathCancer BiologyNatural Killer Cells +15

A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade

Cecile Geuijen, Paul J. Tacken, Liang-Chuan Wang, +38

Nature Communications