Samuël Demin

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus

David C. McGowan, Florence Herschke, Frederik Pauwels et al. · Journal of Medicinal Chemistry · 2016 · 40 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1<i>H</i>-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus

Sandrine Vendeville, Abdellah Tahri, Lili Hu et al. · Journal of Medicinal Chemistry · 2020 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1α,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues

Samuël Demin, Dirk Van Haver, M. Vandewalle et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 17 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Spiro-Azetidine Oxindoles as Long-Acting Injectables for Pre-Exposure Prophylaxis against Respiratory Syncytial Virus Infections

Bart Kesteleyn, Florence Herschke, Nicolas Darville et al. · Journal of Medicinal Chemistry · 2024 · 12 citations

Pharmacy, Pharmacology, Pharmacotherapy +17

Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity

Oscar Mammoliti, Rodrigo J. Carbajo, Laura Pérez‐Benito et al. · Journal of Medicinal Chemistry · 2025 · 12 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17