Lili Hu

Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Pierre Raboisson, Herman de Kock, Åsa Rosenquist et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Design of a Benzodiazepine Scaffold Yields a Potent Allosteric Inhibitor of Hepatitis C NS5B RNA Polymerase

Koen Vandyck, Maxwell D. Cummings, Origène Nyanguile et al. · Journal of Medicinal Chemistry · 2009 · 60 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Design and Optimization of Tricyclic Phtalimide Analogues as Novel Inhibitors of HIV-1 Integrase

Wim G. Verschueren, Inge Dierynck, Katie Amssoms et al. · Journal of Medicinal Chemistry · 2004 · 57 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

2′-Deoxy-2′-spirocyclopropylcytidine Revisited: A New and Selective Inhibitor of the Hepatitis C Virus NS5B Polymerase

Tim H. M. Jonckers, Tse‐I Lin, Christophe Buyck et al. · Journal of Medicinal Chemistry · 2010 · 55 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Nucleotide Prodrugs of 2′-Deoxy-2′-spirooxetane Ribonucleosides as Novel Inhibitors of the HCV NS5B Polymerase

Tim H. M. Jonckers, Koen Vandyck, Leen A. M. Vandekerckhove et al. · Journal of Medicinal Chemistry · 2013 · 44 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17