Nicolas Darville

Intramuscular Administration of Paliperidone Palmitate Extended-Release Injectable Microsuspension Induces a Subclinical Inflammatory Reaction Modulating the Pharmacokinetics in Rats

Nicolas Darville, Marjolein van Heerden, An Vynckier et al. · Journal of Pharmaceutical Sciences · 2014 · 112 citations · Full text

Inflammation, Subclinical Inflammatory Reaction, Anti-inflammatory +5

The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension

Nicolas Darville, Marjolein van Heerden, Dirk Mariën et al. · Journal of Controlled Release · 2016 · 62 citations · Full text

Pharmaceutical Science, Pharmacological Study, Angiogenesis Inhibition +8

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in <i>KMT2A</i>- and <i>NPM1</i>-altered leukemias

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle et al. · Blood · 2024 · 48 citations · Full text

Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the Rat

Nicolas Darville, Marjolein van Heerden, Tim Erkens et al. · Toxicologic Pathology · 2015 · 46 citations · Full text

Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal–cell interactions

Nicolas Darville, Jukka Saarinen, Antti Isomäki et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2015 · 21 citations · Full text

Drug Nano-/microcrystal–cell Interactions, Engineering, Microscopy +11