Oscar Mammoliti

Strategy for the Synthesis of Pyridazine Heterocycles and Their Derivatives

Hassen Bel Abed, Oscar Mammoliti, Omprakash Bande et al. · The Journal of Organic Chemistry · 2013 · 58 citations · Full text

Discovery of<i>N</i>-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4<i>H</i>-thieno[2,3-<i>c</i>]pyran-2-yl)-l<i>H</i>-pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent

Steven E. Van der Plas, Hans Kelgtermans, Tom De Munck et al. · Journal of Medicinal Chemistry · 2017 · 58 citations · Full text

Identification and Characterization of Novel CFTR Potentiators

Maarten Gees, Sara Musch, Steven Van der Plas et al. · Frontiers in Pharmacology · 2018 · 41 citations · Full text

Organophosphorus-catalyzed diaza-Wittig reaction: application to the synthesis of pyridazines

Hassen Bel Abed, Oscar Mammoliti, Omprakash Bande et al. · Organic & Biomolecular Chemistry · 2014 · 34 citations · Full text

Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis

Oscar Mammoliti, Adeline Palisse, Caroline Joannesse et al. · Journal of Medicinal Chemistry · 2021 · 30 citations · Full text