Galapagos (Belgium)

Clinical remission in patients with moderate-to-severe Crohn's disease treated with filgotinib (the FITZROY study): results from a phase 2, double-blind, randomised, placebo-controlled trial

Séverine Vermeire, Stefan Schreiber, Robert Petryka et al. · The Lancet · 2016 · 432 citations

Fitzroy Study, Gastroenterology, Clinical Gastroenterology +4

Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial

Brian G. Feagan, Silvio Danese, Edward V. Loftus et al. · The Lancet · 2021 · 415 citations

Inflammation, Chronic Inflammatory Diseases, Functional Gastrointestinal Disorder +5

Rapamycin decelerates cellular senescence

Zoya N. Demidenko, Elena I. Bukreeva, Valery A. Pospelov et al. · Cell Cycle · 2009 · 389 citations · Full text

Progressive Loss, Aging, Cell Division +13

Global spatial risk assessment of sharks under the footprint of fisheries

Nuno Queiroz, Nicolas E. Humphries, Ana Couto et al. · Nature · 2019 · 376 citations · Full text

Fishery Assessment, Fishery Science, Geography +2

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice

Vladimir N. Anisimov, Mark A. Zabezhinski, Irina G. Popovich et al. · Cell Cycle · 2011 · 344 citations · Full text