Thierry Christophe

Benzothiazinones Kill <i>Mycobacterium tuberculosis</i> by Blocking Arabinan Synthesis

Vadim Makarov, Giulia Manina, Katarı́na Mikus̃ová et al. · Science · 2009 · 722 citations · Full text

Bioorganic Chemistry, Major Btz Target, Antimicrobial Chemotherapy +18

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

Kévin Pethe, Pablo Bifani, Jichan Jang et al. · Nature Medicine · 2013 · 595 citations · Full text

Medicinal Chemistry, Potent Clinical Candidate, Pulmonary Tuberculosis +7

High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

Thierry Christophe, Mary Jackson, Hee Kyoung Jeon et al. · PLoS Pathogens · 2009 · 322 citations · Full text

Antimicrobial Chemotherapy, Drug Resistance, Medicinal Chemistry +21

Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases

Luc Van Rompaey, René Galien, Ellen M. van der Aar et al. · The Journal of Immunology · 2013 · 225 citations · Full text

Immunology, Immunologic Mechanism, Immune Dysregulation +19

The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2

Thierry Christophe, Anna Karlsson, Christophe Dugave et al. · Journal of Biological Chemistry · 2001 · 204 citations · Full text