Jichan Jang

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

Kévin Pethe, Pablo Bifani, Jichan Jang et al. · Nature Medicine · 2013 · 614 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

para-Aminosalicylic Acid Is a Prodrug Targeting Dihydrofolate Reductase in Mycobacterium tuberculosis

Jun Zheng, Eric J. Rubin, Pablo Bifani et al. · Journal of Biological Chemistry · 2013 · 196 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +17

High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

Priscille Brodin, Yannick Poquet, Florence Levillain et al. · PLoS Pathogens · 2010 · 191 citations · Full text

Life Sciences, Microbiology, Molecular Biology +12

Lead Optimization of a Novel Series of Imidazo[1,2-<i>a</i>]pyridine Amides Leading to a Clinical Candidate (Q203) as a Multi- and Extensively-Drug-Resistant Anti-tuberculosis Agent

Sun‐Hee Kang, Ryang Yeo Kim, Min Jung Seo et al. · Journal of Medicinal Chemistry · 2014 · 176 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence

Rachel E. Butler, Priscille Brodin, Jichan Jang et al. · PLoS ONE · 2012 · 71 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17