Sun‐Hee Kang

PA-824 Kills Nonreplicating <i>Mycobacterium tuberculosis</i> by Intracellular NO Release

Ramandeep Singh, Ujjini H. Manjunatha, Helena I. Boshoff et al. · Science · 2008 · 626 citations · Full text

Bioorganic Chemistry, Nitric Oxide, Tuberculosis Prevention +19

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

Kévin Pethe, Pablo Bifani, Jichan Jang et al. · Nature Medicine · 2013 · 595 citations · Full text

Medicinal Chemistry, Potent Clinical Candidate, Pulmonary Tuberculosis +7

High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

Thierry Christophe, Mary Jackson, Hee Kyoung Jeon et al. · PLoS Pathogens · 2009 · 322 citations · Full text

Antimicrobial Chemotherapy, Drug Resistance, Medicinal Chemistry +21

Lead Optimization of a Novel Series of Imidazo[1,2-<i>a</i>]pyridine Amides Leading to a Clinical Candidate (Q203) as a Multi- and Extensively-Drug-Resistant Anti-tuberculosis Agent

Sun‐Hee Kang, Ryang Yeo Kim, Min Jung Seo et al. · Journal of Medicinal Chemistry · 2014 · 173 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Extensively-drug-resistant Anti-tuberculosis Agent +18

Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships

Pilho Kim, Sun‐Hee Kang, Helena I. Boshoff et al. · Journal of Medicinal Chemistry · 2009 · 87 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15