Luc Van Rompaey

Fusion of TEL, the ETS-Variant Gene 6 (ETV6), to the Receptor-Associated Kinase JAK2 as a Result of t(9; 12) in a Lymphoid and t(9; 15; 12) in a Myeloid Leukemia

Pieter J. Peeters, Sophie Raynaud, Jan Cools et al. · Blood · 1997 · 484 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Transformation of hematopoietic cell lines to growth‐factor independence and induction of a fatal myelo‐ and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

Juerg Schwaller, Julie Frantsve‐Hawley, Jon C. Aster et al. · The EMBO Journal · 1998 · 250 citations · Full text

Medicine, Cell Biology, Hematology +13

Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases

Luc Van Rompaey, René Galien, Ellen M. van der Aar et al. · The Journal of Immunology · 2013 · 234 citations · Full text

Life Sciences, Immunology, Pharmacology +12

Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents

Carsten Riether, Thomas Pabst, Sabine Höpner et al. · Nature Medicine · 2020 · 211 citations

Medicine, Hematology, Oncology +14

Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634

Christel Menet, Stephen R. Fletcher, Guy Van Lommen et al. · Journal of Medicinal Chemistry · 2014 · 121 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17