Yuka Koike

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

X. Rosa, Mercedes Prudencio, Yuka Koike et al. · Nature · 2022 · 575 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Sahba Seddighi, Yue Qi, Anna‐Leigh Brown et al. · Science Translational Medicine · 2024 · 158 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration

Wei Shao, Tiffany W. Todd, Yanwei Wu et al. · Science · 2022 · 84 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A

Yuka Koike, Sarah Pickles, Virginia Estades Ayuso et al. · PLoS Biology · 2023 · 73 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation

Akihiro Sugai, Taisuke Kato, Akihide Koyama et al. · Neurobiology of Disease · 2019 · 39 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +11