Sarah Pickles

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

X. Rosa, Mercedes Prudencio, Yuka Koike et al. · Nature · 2022 · 575 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

Jonathon L. Burman, Sarah Pickles, Chunxin Wang et al. · The Journal of Cell Biology · 2017 · 484 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1

Karli K. McDonald, Anaïs Aulas, Laurie Destroismaisons et al. · Human Molecular Genetics · 2011 · 395 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

Yong‐Jie Zhang, Tania F. Gendron, Mark Ebbert et al. · Nature Medicine · 2018 · 339 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Mercedes Prudencio, Jack Humphrey, Sarah Pickles et al. · Journal of Clinical Investigation · 2020 · 257 citations · Full text

Life Sciences, Neurology, Neuroscience +12