Anna‐Leigh Brown

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss et al. · Nature · 2022 · 514 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Mercedes Prudencio, Jack Humphrey, Sarah Pickles et al. · Journal of Clinical Investigation · 2020 · 257 citations · Full text

Life Sciences, Neurology, Neuroscience +12

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Nitin Roper, Anna‐Leigh Brown, Jun S. Wei et al. · Cell Reports Medicine · 2020 · 181 citations · Full text

Medicine, Genetics, Oncology +17

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

Nitin Roper, Moises J. Velez, Alberto Chiappori et al. · Nature Communications · 2021 · 163 citations · Full text

Life Sciences, Immunology, Oncology +17

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Sahba Seddighi, Yue Qi, Anna‐Leigh Brown et al. · Science Translational Medicine · 2024 · 158 citations · Full text

Life Sciences, Neurology, Neuroscience +17