Oscar G. Wilkins

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss et al. · Nature · 2022 · 471 citations · Full text

Highly disordered histone H1−DNA model complexes and their condensates

Abigail L. Turner, Matthew Watson, Oscar G. Wilkins et al. · Proceedings of the National Academy of Sciences · 2018 · 212 citations · Full text

Protein Assembly, Molecular Biology, Protein Phase Separation +18

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Sahba Seddighi, Yue Qi, Anna‐Leigh Brown et al. · Science Translational Medicine · 2024 · 134 citations · Full text

Genetics, Splicing Variant, Cryptic Exons +16

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation

Nicol Birsa, Agnieszka M Ule, Maria Giovanna Garone et al. · Science Advances · 2021 · 63 citations · Full text

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

Roberto Simone, Faiza Javad, Warren Emmett et al. · Nature · 2021 · 55 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Aid Proteostasis +6