Sahba Seddighi

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss et al. · Nature · 2022 · 471 citations · Full text

Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway

Vijay R. Varma, Sudhir Varma, Yang An et al. · Molecular Psychiatry · 2016 · 141 citations · Full text

Neuronal Injury, Neurochemical Biomarkers, Synaptic Signaling +17

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Sahba Seddighi, Yue Qi, Anna‐Leigh Brown et al. · Science Translational Medicine · 2024 · 134 citations · Full text

Genetics, Splicing Variant, Cryptic Exons +16

Social play in juvenile hamsters alters dendritic morphology in the medial prefrontal cortex and attenuates effects of social stress in adulthood.

Cody A. Burleson, Robert W Pedersen, Sahba Seddighi et al. · Behavioral Neuroscience · 2016 · 67 citations · Full text

Developmental Cognitive Neuroscience, Brain Development, Social Play +24

SPARCL1 Accelerates Symptom Onset in Alzheimer’s Disease and Influences Brain Structure and Function During Aging

Sahba Seddighi, Vijay R. Varma, Yang An et al. · Journal of Alzheimer s Disease · 2017 · 42 citations · Full text