Yanwei Wu

Heterochromatin anomalies and double-stranded RNA accumulation underlie <i>C9orf72</i> poly(PR) toxicity

Yong‐Jie Zhang, Lin Guo, Patrick Gonzales et al. · Science · 2019 · 229 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

<i>C9orf72</i> poly(GR) aggregation induces TDP-43 proteinopathy

Casey Cook, Yanwei Wu, Hana M. Odeh et al. · Science Translational Medicine · 2020 · 196 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +6

The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity

Yuan Li, Baohui Chen, Wei Zou et al. · The Journal of Cell Biology · 2016 · 104 citations · Full text

Life Sciences, Biology, Cell Biology +17

Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD

Yanwei Wu, Wei Shao, Tiffany W. Todd et al. · Cell Reports · 2021 · 86 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration

Wei Shao, Tiffany W. Todd, Yanwei Wu et al. · Science · 2022 · 84 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17