Akihide Koyama

Association of HTRA1 Mutations and Familial Ischemic Cerebral Small-Vessel Disease

Kenju Hara, Atsushi Shiga, Toshio Fukutake et al. · New England Journal of Medicine · 2009 · 452 citations · Full text

<i>TDP</i>‐<i>43</i> mutation in familial amyotrophic lateral sclerosis

Akio Yokoseki, Atsushi Shiga, Chun‐Feng Tan et al. · Annals of Neurology · 2008 · 368 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Mendelian Disorder +13

Haploinsufficiency of <i>CSF-1R</i> and clinicopathologic characterization in patients with HDLS

Takuya Konno, Masayoshi Tada, Mari Tada et al. · Neurology · 2013 · 127 citations · Full text

Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1

Atsushi Shiga, Hiroaki Nozaki, Akio Yokoseki et al. · Human Molecular Genetics · 2011 · 112 citations · Full text

Pathology, Serine Proteases, Cerebral Vascular Regulation +24

Distinct molecular mechanisms of <i>HTRA1</i> mutants in manifesting heterozygotes with CARASIL

Hiroaki Nozaki, Taisuke Kato, Megumi Nihonmatsu et al. · Neurology · 2016 · 111 citations