Mandy Madiredjo

A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer

Katrien Berns, Hugo M. Horlings, Bryan T. Hennessy et al. · Cancer Cell · 2007 · 1.6K citations · Full text

Systems Biology, Breast Oncology, Functional Genetic Approach +9

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Katrien Berns, E. Marielle Hijmans, Jasper Mullenders et al. · Nature Cell Biology · 2004 · 1.1K citations · Full text

Large-scale Rnai Screen, Natural Sciences, Molecular Biology +7

The ubiquitin-specific protease USP28 is required for MYC stability

Nikita Popov, Michael Wanzel, Mandy Madiredjo et al. · Nature Cell Biology · 2007 · 480 citations

Protein Function, Myc Stability, Natural Sciences +3

Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition

Atze T. Das, Thijn R. Brummelkamp, Ellen M. Westerhout et al. · Journal of Virology · 2004 · 424 citations · Full text

Rna Interference-mediated Inhibition, Viral Replication, Neurovirology +15

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

Thijn R. Brummelkamp, Armida W. M. Fabius, Jasper Mullenders et al. · Nature Chemical Biology · 2006 · 187 citations · Full text

Shrna Barcode Screen, Mdm2 Inhibitors, Medicine +11