Mandy Madiredjo

A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer

Katrien Berns, Hugo M. Horlings, Bryan T. Hennessy et al. · Cancer Cell · 2007 · 1.6K citations · Full text

Medicine, Molecular Biology, Oncology +17

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Katrien Berns, E. Marielle Hijmans, Jasper Mullenders et al. · Nature Cell Biology · 2004 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

The ubiquitin-specific protease USP28 is required for MYC stability

Nikita Popov, Michael Wanzel, Mandy Madiredjo et al. · Nature Cell Biology · 2007 · 486 citations

Life Sciences, Biochemistry, Molecular Biology +10

Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition

Atze T. Das, Thijn R. Brummelkamp, Ellen M. Westerhout et al. · Journal of Virology · 2004 · 426 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

Thijn R. Brummelkamp, Armida W. M. Fabius, Jasper Mullenders et al. · Nature Chemical Biology · 2006 · 188 citations · Full text

Medicine, Cancer Biology, Oncology +8