Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma

Tobias Otto, Sebastian Horn, Markus Brockmann, +9

Cancer Cell

Neuro-oncologyTumor InnervationHuman NeuroblastomaGliomaAurora A +6

The ubiquitin-specific protease USP28 is required for MYC stability

Nikita Popov, Michael Wanzel, Mandy Madiredjo, +6

Nature Cell Biology

Protein FunctionMyc StabilityNatural SciencesProteasomeMolecular Biology +1

The Ubiquitin Ligase HectH9 Regulates Transcriptional Activation by Myc and Is Essential for Tumor Cell Proliferation

Sovana Adhikary, Federica Marinoni, Andreas Hock, +11

Cell

Transcriptional RegulationSystems BiologyCell RegulationMedicineTranscription Regulation +7

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the <i>telomerase reverse transcriptase</i> promoter during differentiation of HL60 cells

Dawei Xu, Nikita Popov, Mi Hou, +5

Proceedings of the National Academy of Sciences

Epigenetic ChangeMolecular BiologyEpigeneticsTranscriptional RegulationCell Regulation +18

Ubiquitylation of the amino terminus of Myc by SCFβ-TrCP antagonizes SCFFbw7-mediated turnover

Nikita Popov, Christina Schülein, Laura A. Jaenicke, +1

Nature Cell Biology

Protein FunctionSignal TransductionProtein ExpressionMolecular RegulationNatural Sciences +9

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

Markus E. Diefenbacher, Nikita Popov, Sophia M. Blake, +6

Journal of Clinical Investigation

Tumor BiologyUsp28 DeletionGastrointestinal OncologyMedicineImmunology +12

The Histone Deacetylase Inhibitor Trichostatin A Derepresses the Telomerase Reverse Transcriptase (hTERT) Gene in Human Cells

Mi Hou, Xiongbiao Wang, Nikita Popov, +8

Experimental Cell Research

Histone ModificationsChromatinChromatin RemodelingHuman CellsGenetics +7

Fbw7 and Usp28 Regulate Myc Protein Stability in Response to DNA Damage

Nikita Popov, Steffi Herold, Maria Llamazares Prada, +2

Cell Cycle

Tumor cell‐specific inhibition of <scp>MYC</scp> function using small molecule inhibitors of the <scp>HUWE</scp> 1 ubiquitin ligase

Stefanie Peter, Jennyfer Bultinck, Kevin Myant, +14

EMBO Molecular Medicine

Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation

Laura A. Jaenicke, Björn von Eyß, Anne Carstensen, +6

Molecular Cell

Transcriptional RegulationUbiquitin-dependent TurnoverCell RegulationGeneticsGene Regulation +7