The ubiquitin-specific protease USP28 is required for MYC stability

Nikita Popov, Michael Wanzel, Mandy Madiredjo, +6

Nature Cell Biology

Protein FunctionMyc StabilityNatural SciencesProteasomeMolecular Biology +1

Negative Regulation of the Mammalian UV Response by Myc through Association with Miz-1

Steffi Herold, Michael Wanzel, Vincent Beuger, +7

Molecular Cell

Signal TransductionCell RegulationMolecular RegulationPhotocarcinogenesisGene Expression +9

Compassionate use of sorafenib in FLT3-ITD–positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation

Stephan Metzelder, Ying Wang, Ellen Wollmer, +7

Blood

mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability

Niklas Gremke, Pierfrancesco Polo, Aaron Dort, +9

Nature Communications

Druggable Metabolic VulnerabilityTumor BiologyMitophagySystems BiologyCell Autophagy +13

A ribosomal protein L23-nucleophosmin circuit coordinates Miz1 function with cell growth

Michael Wanzel, Annika C. Russ, Daniela Kleine‐Kohlbrecher, +3

Nature Cell Biology

Miz1 FunctionProtein FunctionCell DivisionNatural SciencesMolecular Biology +7

Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5

Fotini Vogiatzi, Dominique T. Brandt, Jean Schneikert, +16

Proceedings of the National Academy of Sciences

Cancer ResearchP53 Gof MutationsMedicineTumor SuppressionApoptosis +12

Incidence and severity of electric scooter related injuries after introduction of an urban rental programme in Vienna: a retrospective multicentre study

Timon Moftakhar, Michael Wanzel, Alexander Vojcsik, +5

Archives of Orthopaedic and Trauma Surgery

CRISPR-Cas9–based target validation for p53-reactivating model compounds

Michael Wanzel, Jonas B. Vischedyk, Miriam P. Gittler, +11

Nature Chemical Biology

Molecular BiologyCrispr-cas9–based Target ValidationGene EditingGenome EditingMedicine +2

Akt and 14-3-3η regulate Miz1 to control cell-cycle arrest after DNA damage

Michael Wanzel, Daniela Kleine‐Kohlbrecher, Steffi Herold, +5

Nature Cell Biology

ChromatinGenome InstabilityTranscriptional RegulationDna DamageCell Regulation +10

p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo

Oleg Timofeev, Katharina Schlereth, Michael Wanzel, +6

Cell Reports

Genome InstabilityOncogenic AgentMedicineTumor SuppressionApoptosis +12