Armida W. M. Fabius

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Şevin Turcan, Daniel Rohle, Anuj Goenka et al. · Nature · 2012 · 1.9K citations · Full text

Neuro-oncology, Somatic Variant, Tumor Heterogeneity +11

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine

Şevin Turcan, Armida W. M. Fabius, Alexandra Borodovsky et al. · Oncotarget · 2013 · 233 citations · Full text

Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence

Şevin Turcan, Vladimir Makarov, Julián Taranda et al. · Nature Genetics · 2017 · 224 citations · Full text

Chromatin, Chromatin Structure, Chromatin Remodeling +6

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

Thijn R. Brummelkamp, Armida W. M. Fabius, Jasper Mullenders et al. · Nature Chemical Biology · 2006 · 187 citations · Full text

Shrna Barcode Screen, Mdm2 Inhibitors, Medicine +11

5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft

Alexandra Borodovsky, Vafi Salmasi, Şevin Turcan et al. · Oncotarget · 2013 · 153 citations · Full text

5-Azacytidine Reduces Methylation, High-grade Gliomas, Cancer Biology +23