Hugo M. Horlings

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

Rajnish A. Gupta, Nilay Shah, Jeewon Kim et al. · Nature · 2010 · 5.2K citations · Full text

Non-coding Rna Hotair, Chromatin, Engineering +14

AACR Project GENIE: Powering Precision Medicine through an International Consortium

Fabrice André, Mónica Arnedos, Alexander S. Baras et al. · Cancer Discovery · 2017 · 1.9K citations · Full text

A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer

Katrien Berns, Hugo M. Horlings, Bryan T. Hennessy et al. · Cancer Cell · 2007 · 1.6K citations · Full text

Systems Biology, Breast Oncology, Functional Genetic Approach +9

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

Hanjie Li, Anne M. van der Leun, Ido Yofe et al. · Cell · 2018 · 1.1K citations · Full text

Cancer Immunosurveillance, Human Melanoma, T-regulatory Cell +8

An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer

Katherine Stemke‐Hale, Ana M. González-Angulo, Aňa Lluch et al. · Cancer Research · 2008 · 1K citations · Full text

Breast Oncology, Engineering, Integrative Genomic +16