Anne M. van der Leun

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

Hanjie Li, Anne M. van der Leun, Ido Yofe et al. · Cell · 2018 · 1.1K citations · Full text

Life Sciences, Immunology, Oncology +16

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma

Joris L. Vos, Joris B.W. Elbers, Oscar Krijgsman et al. · Nature Communications · 2021 · 336 citations · Full text

Pharmacy, Oncology, Pharmacotherapy +17

Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment

Anne M. van der Leun, Joleen J.H. Traets, Joris L. Vos et al. · Cancer Discovery · 2023 · 42 citations · Full text

Life Sciences, Immunology, Oncology +17

Feasibility and toxicity of neoadjuvant nivolumab with or without ipilimumab prior to extensive (salvage) surgery in patients with advanced head and neck cancer (the IMCISION trial, NCT03003637).

Charlotte L. Zuur, Joris B.W. Elbers, Joris L. Vos et al. · Journal of Clinical Oncology · 2019 · 20 citations

Medicine, Oncology, Surgery +17

LBA40 Neoadjuvant nivolumab and nivolumab plus ipilimumab induce (near-) complete responses in patients with head and neck squamous cell carcinoma: The IMCISION trial

L. Zuur, Joris L. Vos, Joris B.W. Elbers et al. · Annals of Oncology · 2020 · 20 citations · Full text

Pharmacy, Immunology, Oncology +16