Megan S. Keiser

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo

Alex Mas Monteys, Shauna Ebanks, Megan S. Keiser et al. · Molecular Therapy · 2017 · 309 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Broad Therapeutic Benefit After RNAi Expression Vector Delivery to Deep Cerebellar Nuclei: Implications for Spinocerebellar Ataxia Type 1 Therapy

Megan S. Keiser, Ryan L. Boudreau, Beverly L. Davidson · Molecular Therapy · 2014 · 80 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Toxicity after AAV delivery of RNAi expression constructs into nonhuman primate brain

Megan S. Keiser, Paul T. Ranum, Carolyn M. Yrigollen et al. · Nature Medicine · 2021 · 73 citations · Full text

Pharmacy, Molecular Biology, Neuroscience +13

APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease

Rosemary J. Jackson, Megan S. Keiser, Jonah C Meltzer et al. · Molecular Therapy · 2024 · 69 citations · Full text

Life Sciences, Neurology, Neuroscience +17

RNAi prevents and reverses phenotypes induced by mutant human ataxin‐1

Megan S. Keiser, Alejandro Mas Monteys, Romuald Corbau et al. · Annals of Neurology · 2016 · 56 citations · Full text

Life Sciences, Genetics, Neuroscience +17