Alex Mas Monteys

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

Jodi L. McBride, Ryan L. Boudreau, Scott Q. Harper et al. · Proceedings of the National Academy of Sciences · 2008 · 606 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Engineering +15

Structure and activity of putative intronic miRNA promoters

Alex Mas Monteys, Ryan M. Spengler, Ji Wan et al. · RNA · 2010 · 366 citations · Full text

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo

Alex Mas Monteys, Shauna Ebanks, Megan S. Keiser et al. · Molecular Therapy · 2017 · 302 citations · Full text

Engineering, In Vivo Gene Therapy, Genetics +18

Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes

John H. Lee, Luis Tecedor, Yong Hong Chen et al. · Neuron · 2014 · 166 citations · Full text

Neurodegenerative Diseases, Genetics, Disease Phenotypes +7

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

Ryan L. Boudreau, Alex Mas Monteys, Beverly L. Davidson · RNA · 2008 · 162 citations · Full text

Rna Processing, Systems Biology, Functional Genomics +15