Scott Q. Harper

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

Scott Q. Harper, Patrick D. Staber, Xiaohua He et al. · Proceedings of the National Academy of Sciences · 2005 · 674 citations · Full text

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease

Nicolle H. Packer, Yi Xing, Scott Q. Harper et al. · Journal of Neuroscience · 2008 · 669 citations · Full text

Genetics, Polyglutamine Expansions, Epigenetics +18

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia

Haibin Xia, Qinwen Mao, Steven Eliason et al. · Nature Medicine · 2004 · 651 citations

Neurodegenerative Diseases, Molecular Neuroscience, Degenerative Pathology +8

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

Jodi L. McBride, Ryan L. Boudreau, Scott Q. Harper et al. · Proceedings of the National Academy of Sciences · 2008 · 606 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Engineering +15

Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy

Scott Q. Harper, Michael A. Hauser, Christiana DelloRusso et al. · Nature Medicine · 2002 · 559 citations

Gene Therapies, Skeletal Muscle, Duchenne Muscular Dystrophy +7