Ryan L. Boudreau

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

Jodi L. McBride, Ryan L. Boudreau, Scott Q. Harper et al. · Proceedings of the National Academy of Sciences · 2008 · 608 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Artificial MicroRNAs as siRNA Shuttles: Improved Safety as Compared to shRNAs In vitro and In vivo

Ryan L. Boudreau, Inês Martins, Beverly L. Davidson · Molecular Therapy · 2008 · 352 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice

Ryan L. Boudreau, Jodi L. McBride, Inês Martins et al. · Molecular Therapy · 2009 · 335 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency

Colleen S. Stein, Pooja Jadiya, Xiaoming Zhang et al. · Cell Reports · 2018 · 273 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease

Jodi L. McBride, Mark R. Pitzer, Ryan L. Boudreau et al. · Molecular Therapy · 2011 · 245 citations · Full text

Life Sciences, Neurology, Neuroscience +17