Nature Medicine · 2004 · 651 citations · 24 references
Life SciencesMolecular GeneticsNeuroscienceMolecular NeurobiologyMolecular NeuroscienceNeurodegenerationMolecular Basis Of NeurodegenerationMolecular NeurogeneticsNeurodegenerative DiseasesNeurodegenerative DisordersRna InterferenceSpinocerebellar AtaxiasHereditary AtaxiasNeuronal DysfunctionPolyglutamine DiseasesSpinocerebellar Ataxia GeneticsSpinocerebellar Ataxia Models
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Functional siRNAs and miRNAs Exhibit Strand Bias
Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena · Cell · 2003 · 2.6K citations · Full text
Rational siRNA design for RNA interference
Angela Reynolds, Devin Leake, Queta Boese et al. · Nature Biotechnology · 2004 · 2.1K citations
Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1
Harry T. Orr, Ming‐Yi Chung, Sandro Banfi et al. · Nature Genetics · 1993 · 1.7K citations
Ataxin-1 Nuclear Localization and Aggregation
Ivan A. Klement, Pamela J. Skinner, Michael D. Kaytor et al. · Cell · 1998 · 962 citations · Full text
siRNA-mediated gene silencing in vitro and in vivo
Haibin Xia, Qinwen Mao, Henry L. Paulson et al. · Nature Biotechnology · 2002 · 880 citations