Angela Reynolds

Functional siRNAs and miRNAs Exhibit Strand Bias

Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena · Cell · 2003 · 2.6K citations · Full text

Functional Sirnas, Genetics, Rna Biology +6

Rational siRNA design for RNA interference

Angela Reynolds, Devin Leake, Queta Boese et al. · Nature Biotechnology · 2004 · 2.1K citations

Rational Sirna Design, Natural Sciences, Rna Biology +7

3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets

Amanda Birmingham, Emily M. Anderson, Angela Reynolds et al. · Nature Methods · 2006 · 880 citations

Transcriptional Regulation, Functional Genomics, Natural Sciences +14

Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing

Aimee L. Jackson, Julja Burchard, Devin Leake et al. · RNA · 2006 · 781 citations · Full text

Rna Processing, Transcriptional Regulation, Rna Duplex +15

Off-target effects by siRNA can induce toxic phenotype

Yuriy Fedorov, Emily M. Anderson, Amanda Birmingham et al. · RNA · 2006 · 489 citations · Full text

Genetics, Epigenetics, Toxicological Mechanism +16