Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus

Dimitri Lavillette, Eve‐Isabelle Pécheur, Peggy Donot, +6

Journal of Virology

Pyrazole NNRTIs 4: Selection of UK-453,061 (lersivirine) as a Development Candidate

Charles E. Mowbray, Catherine Burt, Romuald Corbau, +10

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryHeterocyclicPyrazole Nnrtis 4Development Candidate +10

Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1

Romuald Corbau, Julie Mori, Chris Phillips, +12

Antimicrobial Agents and Chemotherapy

ImmunologyMolecular BiologyPharmacotherapyAntiviral DrugExcellent Selectivity +14

Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays

Lyn H. Jones, Gill Allan, Oscar Barba, +13

Journal of Medicinal Chemistry

Combinatorial ChemistryMolecular BiologyPharmacotherapyAntiviral DrugMedicinal Chemistry +14

RNAi prevents and reverses phenotypes induced by mutant human ataxin‐1

Megan S. Keiser, Alejandro Mas Monteys, Romuald Corbau, +2

Annals of Neurology

Biochemical Activities of Minute Virus of Mice Nonstructural Protein NS1 Are Modulated In Vitro by the Phosphorylation State of the Polypeptide

Jürg P. F. Nüesch, Romuald Corbau, Peter Tattersall, +1

Journal of Virology

Regulation of MVM NS1 by Protein Kinase C: Impact of Mutagenesis at Consensus Phosphorylation Sites on Replicative Functions and Cytopathic Effects

Romuald Corbau, Valérie Duverger, Jean Rommelaere, +1

Virology

Signal TransductionProtein Kinase CMvm Ns1Cell RegulationReceptor Tyrosine Kinase +7

Replicative Functions of Minute Virus of Mice NS1 Protein Are Regulated In Vitro by Phosphorylation through Protein Kinase C

Jürg P. F. Nüesch, Sabine Dettwiler, Romuald Corbau, +1

Journal of Virology

Regulation of Minute Virus of Mice NS1 Replicative Functions by Atypical PKCλ In Vivo

Jürg P. F. Nüesch, Sylvie Lachmann, Romuald Corbau, +1

Journal of Virology

Viral ReplicationViral Polymerase MechanismViral PathogenesisImmunologyMolecular Biology +15

Preclinical evaluation of FLT190, a liver-directed AAV gene therapy for Fabry disease

Jey M Jeyakumar, Azadeh Kia, Lawrence C. S. Tam, +18

Gene Therapy