Spark Therapeutics (United States)

Statistics

Publications

625

Citations

58.1K

Authors

Location

Philadelphia, United States

Spark Therapeutics (United States) is a company institution in Philadelphia, United States known for medicine, gene therapy, and adeno-associated viral vectors.

Homepage ROR

Top concepts

MedicineGene TherapyAdeno-associated Viral VectorsHematologyLife SciencesImmunologyGene DeliveryHemostasisTransfusion MedicineAdenoviral Vectors

Publications

625

Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial

Stephen R. Russell, Jean Bennett, Jennifer Wellman et al. · The Lancet · 2017 · 1.9K citations

Medicine, Ophthalmology, Vision Science +14

Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant

Lindsey A. George, Spencer K. Sullivan, Adam Giermasz et al. · New England Journal of Medicine · 2017 · 759 citations · Full text

Medicine, Hematology, Molecular Medicine +15

Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial

Jean Bennett, Jennifer Wellman, Kathleen Marshall et al. · The Lancet · 2016 · 456 citations · Full text

Medicine, Genetics, Ophthalmology +16

Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation–Associated Inherited Retinal Dystrophy

Albert M. Maguire, Stephen R. Russell, Jennifer Wellman et al. · Ophthalmology · 2019 · 391 citations · Full text

Medicine, Ophthalmology, Vision Science +16

IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies

Christian Leborgne, Elena Barbon, J M Alexander et al. · Nature Medicine · 2020 · 319 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +9

1–5 of 625

Authors

KZ
Kathleen Z. Reape
Spark Therapeutics (United States), United States
44 publications · 1.2K citations
14
h-index
VG
Vijaya G. Tirunagaru
Spark Therapeutics (United States), United States
64 publications · 672 citations
11
h-index
TO
Thomas O’Connell
Spark Therapeutics (United States), United States
37 publications · 313 citations
7
h-index
FH
Frank H. Riddle
Spark Therapeutics (United States), United States
26 publications · 421 citations
6
h-index
JL
Jewlya Lynn
Spark Therapeutics (United States), United States
13 publications · 64 citations
5
h-index

1–5 of 45