Concepedia
Statistics
Publications
21
Citations
2.4K
H-Index
18
Active since
1984
Affiliations
University of Michigan(Current)
Indiana University – Purdue University Indianapolis
University of Pennsylvania
Memorial Sloan Kettering Cancer Center
University of Burdwan
Trupta Purohit is an author at University of Michigan specializing in medicine, natural sciences, and cell biology.
Top concepts
MedicineNatural SciencesCell BiologyChemical BiologyMolecular BiologyEngineeringMolecular DockingPhysicsBiochemistryDrug Discovery
Publications per year
1984–2024
Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin
Gary J. Fisher, Taihao Quan, Trupta Purohit et al. · American Journal Of Pathology · 2008 · 446 citations · Full text
Fibrosis, Aged Human Skin, Cutaneous Biology +10
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
Jolanta Grembecka, Shihan He, Aibin Shi et al. · Nature Chemical Biology · 2012 · 429 citations
Hematological Malignancy, Tumor Biology, Mixed-phenotype Acute Leukemia +9
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo
Dmitry Borkin, Shihan He, Hongzhi Miao et al. · Cancer Cell · 2015 · 394 citations · Full text
Hematological Malignancy, Mll Leukemia, Pharmacologic Inhibition +9
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia
Szymon Kłossowski, Hongzhi Miao, Katarzyna Kempińska et al. · Journal of Clinical Investigation · 2019 · 223 citations · Full text
Npm1-mutated Models, Hematological Malignancy, Systems Biology +13
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia
Aibin Shi, Marcelo J. Murai, Shihan He et al. · Blood · 2012 · 198 citations · Full text
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